mAB Drugs
Email Kathy


Surfing Biotech's Second Wave: Monoclonal Antibody drugs
September 15, 2009

 

Know your Drugs!

 

Drug Name MOA Market

 

 

 Blocks CD3+T-cell activation  

1.

 

and if that doesn't work...

 

2.

 

and as another option

3.

 CD20+ B cells Non-Hodgkins Lymphoma  

 

 

 Her2 receptor overexpression  

1.

 

2.

 

3.

 

 

 We all scavenge excess TNF  

1.

2.

 Blocks IL-2 mediated T-cell activation  

 

 

 CD52 antigen B-cell chronic lymphocytic leukemia (B-CLL)  
  CD33+ antigen of
Leukemic blast cells (AML)		  

 

1.

 

2.

 

 

 Both are VEGF Inhibitors; 2 different indications  
  Decreases IgE in the blood and prevents binding to mast cells ass'd with allergy-related asthma  

 

Metastatic colo-rectal cancer: 2 drugs, 2 different approaches:

1.

 

2.

 

 

 

 

 

 

 

 

Thank you MICE for your contributions to the mAb process....