Deem A., Keszthelyi A., Blackgrove T., Vayl A., Coffey B., Mathur R., Chabes A., Malkova A. “Break-Induced Repalication Is Highly Inaccurate.” PLoS Biology. (2011), 9(2).

Chung Y., Zhu, Papusha A., MalkovaA., and Ira.G. “Elimination of processive resection at DNA double-strand breaks leads to de novo telomere formation and enhances gene targeting”, PLoS Genetics. (2010), 13;6(5)

Westmoreland J, Ma W, Yan Y, Van Hulle K, Malkova A, Resnick MA. “RAD50 is required for efficient initiation of resection and recombinational repair at random, gamma-induced double-strand break ends”.  PLoS Genet. (2009), 5:1-18.

Downing B., Morgan R., VanHulle K., Deem A., and Malkova A.  “Large inverted repeats in the vicinity of a single double-strand break strongly affect repair in yeast diploids lacking Rad51” Mutation Research, (2008), 645:9-18.

Deem A., Barker K., VanHulle K., Downing B., Vayl A., and Malkova A.  “Defective break-induced replication leads to half-crossovers in Saccharomyces cerevisiae.”  Genetics, (2008), 179: 1845-1860.

VanHulle K., Lemoine F. J., Narayanan V., Downing B., Hull K., McCullough C., Bellinger M., Lobachev K., Petes T. D., and Malkova A.  “Inverted DNA repeats channel repair of distant double-strand breaks into chromatid fusions and chromosomal rearrangements.” Mol. Cell. Biol., (2007), 27: 2601-2614.

Malkova A., Naylor A.L., Yamaguchi M., Ira G., and Haber J.  “RAD51-dependent break-induced replication differs in kinetics and checkpoint responses from RAD51-mediated gene conversion.” Mol. Cell. Biol., (2005), 25: 933-944.

Malkova A., Swanson J., German M., McCusker J.H., Housworth E.A., Stahl F.W., and Haber J.E. “Gene conversion and crossing-over along the 405-kb left arm of Saccharomyces cerevisiae chromosome VII.” Genetics, (2004), 168: 49-63.

Ira G., Malkova A., Liberi G., Foiani M., and Haber J.E.  “Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast.” Cell, (2003), 115: 401-11.

Lee S.-E., Pellicioli A., Sugawara N., Vaze M., Malkova A., Foiani M., and Haber J.  “Yeast Rad52 and Rad51 recombination proteins define a second pathway of DNA damage assessment in response to a single double-strand break.”  Mol. Cell. Biol., (2003), 23: 8913-8923.

Malkova A., Signon L., Schaefer C., Naylor M., Murakami H., Ohta K., Newlon C., and Haber J.  “RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site.”  Genes Dev., (2001), 15: 1055-1060.

Signon L., Malkova A., Naylor M., Klein H., and Haber J.  “Genetic requirements for break-induced replication repair of a chromosomal double-strand break.” Mol. Cell. Biol., (2001), 21: 2048-2056.

Lee S.-E., Pellicioli A., Malkova A., Foiani M., and. Haber J.E.The Saccharomyces recombination protein Tid1p is required for adaptation from G2/M arrest induced by a single double-strand break.”  Curr. Biol., (2001), 11: 1053-1057.

Malkova A., Klein F., Leung W.-Y., and Haber J.E.  HO endonuclease-induced recombination in yeast meiosis resembles Spo11-induced events.” Proc. Natl. Acad. Sci. USA, (2000), 97: 14500-14505.

Lee S.E., Pellicioli A., Demeter J., Vaze M.P., Gasch A.P., Malkova A., Brown P.O., Botstein D., Stearns T., Foiani M., and Haber J.E.  “Arrest, Adaptation, and Recovery following a chromosome double-strand break in Saccharomyces cerevisiae.”  Cold Spring Harbor Symposia on Quantitative Biology, Vol. LXV, Cold Spring Harbor Laboratory Press, (2000), 303-313.

Leung W., Malkova A., and Haber J.E.  “Gene targeting by linear duplex DNA frequently occurs by assimilation of a single strand that is subject to preferential mismatch correction.” Proc. Natl. Acad. Sci. USA, (1997), 94: 6851-6856.

Malkova A., Ivanov E.L., and Haber J.E.  “Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication.”  Proc. Natl. Acad. Sci. USA, (1996), 93: 7131-7136.

Malkova A., Ross D., Dawson M., Hoekstra F., and Haber, J. E.  “Meiotic recombination initiated by a double-strand break in rad50 delta yeast cells otherwise unable to initiate meiotic recombination.”  Genetics, (1996), 143: 741-754.

Gordenin D.A., Lobachev K.S., Degtyareva N.P., Malkova A.L, Perkins E, and Resnick M.A. “Inverted DNA repeats: a source of genomic instability.”  Mol. Cell. Biol., (1993), 13: 5315- 5322.

Gordenin D.A., Malkova A.L., Petersen A., Kulikov V.N., Pavlov Y.I., Perkins E., and Resnick M.A.  “Transposon Tn5 excision in yeast: the influence of DNA polymerases alpha, delta, epsilon and repair genes.”  Proc. Natl. Acad. Sci. USA, (1992), 89: 3785-3789.

Gordenin D.A., Prosciavicus Y.Y., Malkova A.L., Trofimova M.I., and Petersen A. “Yeast mutants with increased bacterial transposon Tn5 excision.” Yeast, (1991), 7: 37-59.


Anna Malkova Ph.D.

Genetics / Mechanism of DNA Repair and Recombination.

Department of Biology